Yoga Can Reverse DNA Changes, Reducing Risk of Cancer and Depression: Study

Yoga has long being touted as the one-stop solution to a healthy body, mind and soul. This ancient form of physical exercise works on different parts of the body to boost its overall function and well-being. Now a new study done by researchers from Universities of Coventry and Radboud states that yoga can also affect molecular reactions in the DNA and prevent risks of certain ailments. Mind-body interventions (MBIs) such as meditation, yoga and Tai Chi can help reduce risk of depression and cancer by reversing the molecular reactions in DNA if practiced on a daily basis.

Stress is a common feature in our urban lifestyle. It is also one of the leading factors in causing various kinds of diseases. When a person is exposed to a stressful event, their sympathetic nervous system (SNS) - the system responsible for the 'fight-or-flight' response - is triggered, in turn increasing production of a molecule called nuclear factor kappa B (NF-kB), which regulates how our genes are expressed.

NF-kB translates stress by activating genes to produce proteins called cytokines that cause inflammation at cellular level - a reaction that is useful as a short-lived fight-or-flight reaction, but if persistent, leads to a higher risk of cancer, accelerated aging and psychiatric disorders like depression.

(Also read: Yoga for Depression: 5 Effective Poses That Can Curb the Negativity)
 

^{Yoga can help reduce risk of depression and cancer by reversing the molecular reactions in DNA; Image credit: Istock}

The researchers through 18 studies - featuring 846 participants over 11 years - revealed a pattern in the molecular changes which happen to the body as a result of the MBIs, and how those changes benefit our mental and physical health. They explained the way that genes activate to produce proteins, which influence the biological make-up of the body, the brain and the immune system.

According to the study, people who practise MBIs exhibit the opposite effect - namely a decrease in production of NF-kB and cytokines, leading to a reversal of the pro-inflammatory gene expression pattern and a reduction in the risk of inflammation-related diseases and conditions.

Lead investigator Ivana Buric said that millions of people around the world already enjoy the health benefits of mind-body interventions like yoga or meditation, but what perhaps these people do not realise is that these benefits begin at a molecular level and can change the way our genetic code goes about its business.

"These activities are leaving what we call a molecular signature in our cells, which reverses the effect that stress or anxiety would have on the body by changing how our genes are expressed. Put simply, the MBIs cause the brain to steer our DNA processes along a path which improves our well-being."

The research is published in the journal Frontiers in Immunology.